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Oliver Buchannon
Marco Lolaico

DNA nanotech researcher, writing Plenty of Room to always bring you the coolest papers!

Synthetic Biology

Biological Quantum Sensors: Fluorescent Proteins Transform Biology!

Mar 12, 2026

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10 min read

Biological Quantum Sensors: Fluorescent Proteins Transform Biology!

Directed evolution converts a fluorescent protein into a genetically encoded quantum sensor.

Marco Lolaico
Marco Lolaico

Drug delivery

+1

DNA Origami Boosts Anti-HIV Antibodies: Vaccine Breakthrough!

Mar 5, 2026

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10 min read

DNA Origami Boosts Anti-HIV Antibodies: Vaccine Breakthrough!

DNA origami enhances production of rare anti-HIV antibodies by rewiring immune competition.

Marco Lolaico
Marco Lolaico

Genome Editing Tools

+1

Armored Viruses: Mineral Shells Deliver RNA Editors to Treat Sepsis!

Feb 26, 2026

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10 min read

Armored Viruses: Mineral Shells Deliver RNA Editors to Treat Sepsis!

Mineral shells help viruses evade immunity, deliver RNA editors, and treat sepsis in mice

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Designer RNA Tiles: Programmable Nanostructures Inside Cell Nuclei!

Feb 19, 2026

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8 min read

Designer RNA Tiles: Programmable Nanostructures Inside Cell Nuclei!

Programmable RNA structures assemble inside living cell nuclei

Marco Lolaico
Marco Lolaico

Synthetic Biology

RNA TimeVaults: Capturing Cellular Decision Dynamics!

Feb 12, 2026

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9 min read

RNA TimeVaults: Capturing Cellular Decision Dynamics!

A molecular hard drive engineered to store RNA states in living cells.

Marco Lolaico
Marco Lolaico

Synthetic Biology

Sidewinder Rewrites DNA Assembly Rules With Designed DNA Junctions!

Feb 5, 2026

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10 min read

Sidewinder Rewrites DNA Assembly Rules With Designed DNA Junctions!

A new assembly method builds complex DNA without sequence or length constraints

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

DNA Origami Needles: Virus-Inspired Nanostructures for Drug Delivery!

Jan 29, 2026

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10 min read

DNA Origami Needles: Virus-Inspired Nanostructures for Drug Delivery!

Engineering Virus-Like Delivery Using Programmable DNA Structures

Marco Lolaico
Marco Lolaico

AI protein design

AI-Designed Enzyme Atoms: RFdiffusion2 Crafts Catalytic Proteins!

Jan 22, 2026

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11 min read

AI-Designed Enzyme Atoms: RFdiffusion2 Crafts Catalytic Proteins!

Designing functional enzymes by placing catalytic atoms with RFdiffusion2

Marco Lolaico
Marco Lolaico

Genome Editing Tools

Epigenetic Editors: CRISPR's Geneless Gene Control Revolution!

Jan 15, 2026

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10 min read

Epigenetic Editors: CRISPR's Geneless Gene Control Revolution!

How a new delivery system and epigenetic editors control genes without cutting DNA

Marco Lolaico
Marco Lolaico

AI protein design

AI-Designed Enzyme Engineering: Machine Learning Catalyzes Biotech Breakthroughs!

Jan 8, 2026

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10 min read

AI-Designed Enzyme Engineering: Machine Learning Catalyzes Biotech Breakthroughs!

How catalytic motifs and protein backbones can be assembled into functional enzymes from scratch

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

DNA Trivalent Binders: DNA Nanotechnology Meets Viral Geometry!

Jan 2, 2026

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10 min read

DNA Trivalent Binders: DNA Nanotechnology Meets Viral Geometry!

Evolving trivalent DNA binders to match viral protein geometry

Marco Lolaico
Marco Lolaico
2025 Wrapped

Dec 23, 2025

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8 min read

2025 Wrapped

The "best" articles of the year!

Marco Lolaico
Marco Lolaico

Synthetic Biology

+1

AI-Designed DNA Binders: Machine Learning Crafts Novel Proteins!

Dec 18, 2025

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10 min read

AI-Designed DNA Binders: Machine Learning Crafts Novel Proteins!

Designing sequence-specific DNA-binding proteins entirely from scratch

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

DNA Origami Membranes: Molecular Mimicry Rewrites Cellular Architecture!

Dec 11, 2025

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10 min read

DNA Origami Membranes: Molecular Mimicry Rewrites Cellular Architecture!

Engineered DNA barrels self-organize into flexible monolayers that behave like synthetic membranes.

Marco Lolaico
Marco Lolaico

AI for genome

AI-Born Genes: Machine Learning Rewrites Genomics!

Dec 4, 2025

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10 min read

AI-Born Genes: Machine Learning Rewrites Genomics!

How a Genomic Foundation Model Turns Evolutionary Patterns into Brand-New Functional Genes

Marco Lolaico
Marco Lolaico

Synthetic Biology

+1

Cell-Electronics Hybrids: Immune Cells For Neural Modulation!

Nov 27, 2025

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10 min read

Cell-Electronics Hybrids: Immune Cells For Neural Modulation!

Immune cells carry micro-circuits into the brain for neural activation, with no surgery.

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

DNA Flowers: Shape-Shifting Materials Bloom with Biomimetic Magic!

Nov 20, 2025

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10 min read

DNA Flowers: Shape-Shifting Materials Bloom with Biomimetic Magic!

How Programmable DNA–Crystal Hybrids Learn to Open, Close, and Change Shape

Marco Lolaico
Marco Lolaico

AI protein design

AI-Designed Antibodies: RFdiffusion Redefines Molecular Medicine!

Nov 13, 2025

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10 min read

AI-Designed Antibodies: RFdiffusion Redefines Molecular Medicine!

From target to binder: how machine learning is reinventing the way we make antibodies.

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Budding DNA Origami: Crafting Synthetic Cell Membrane Systems!

Nov 6, 2025

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9 min read

Budding DNA Origami: Crafting Synthetic Cell Membrane Systems!

Mimicking cellular budding with programmable DNA scaffolds.

Marco Lolaico
Marco Lolaico

Synthetic Biology

+1

Quantum Biology Breakthrough: Fluorescent Proteins as Quantum Sensors!

Oct 30, 2025

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11 min read

Quantum Biology Breakthrough: Fluorescent Proteins as Quantum Sensors!

Fluorescent proteins become the first biological quantum sensors, bridging physics and biology.

Marco Lolaico
Marco Lolaico

Drug delivery

AI-Designed Lipid Nanoparticles: Machine Learning Boosts RNA Medicine!

Oct 23, 2025

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9 min read

AI-Designed Lipid Nanoparticles: Machine Learning Boosts RNA Medicine!

Machine learning steps in to craft better lipid carriers for RNA medicines

Marco Lolaico
Marco Lolaico

AI protein design

Computer-Designed Light-Switch Proteins: Controlling Biology with Photons!

Oct 16, 2025

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9 min read

Computer-Designed Light-Switch Proteins: Controlling Biology with Photons!

Designing proteins that assemble and fall apart, controlled by light

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

DNA Nanocages: Synthetic Organelles Redefine Cellular Engineering!

Oct 10, 2025

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8 min read

DNA Nanocages: Synthetic Organelles Redefine Cellular Engineering!

DNA nanocages turn extracellular vesicles into synthetic organelles

Marco Lolaico
Marco Lolaico
Express Edition, Plus Personal News!

Oct 2, 2025

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4 min read

Express Edition, Plus Personal News!

Weddings, Synthetic Protein and DNA origami.

Marco Lolaico
Marco Lolaico

AI protein design

AI-Designed Protein Binders: BindCraft Revolutionizes Molecular Design!

Sep 25, 2025

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10 min read

AI-Designed Protein Binders: BindCraft Revolutionizes Molecular Design!

BindCraft turns hallucinations into powerful protein-binder designs

Marco Lolaico
Marco Lolaico
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