Marco Lolaico

Marco Lolaico

DNA nanotech researcher, writing Plenty of Room to always bring you the coolest papers!

Synthetic BiologySynthetic Biology
RNA TimeVaults: Capturing Cellular Decision Dynamics!

RNA TimeVaults: Capturing Cellular Decision Dynamics!

A molecular hard drive engineered to store RNA states in living cells.

Marco Lolaico
Marco Lolaico
Synthetic BiologySynthetic Biology
Sidewinder Rewrites DNA Assembly Rules With Designed DNA Junctions!

Sidewinder Rewrites DNA Assembly Rules With Designed DNA Junctions!

A new assembly method builds complex DNA without sequence or length constraints

Marco Lolaico
Marco Lolaico
DNA/RNA nanotechDNA/RNA nanotech
DNA Origami Needles: Virus-Inspired Nanostructures for Drug Delivery!

DNA Origami Needles: Virus-Inspired Nanostructures for Drug Delivery!

Engineering Virus-Like Delivery Using Programmable DNA Structures

Marco Lolaico
Marco Lolaico
AI protein designAI protein design
AI-Designed Enzyme Atoms: RFdiffusion2 Crafts Catalytic Proteins!

AI-Designed Enzyme Atoms: RFdiffusion2 Crafts Catalytic Proteins!

Designing functional enzymes by placing catalytic atoms with RFdiffusion2

Marco Lolaico
Marco Lolaico
Genome Editing ToolsGenome Editing Tools
Epigenetic Editors: CRISPR's Geneless Gene Control Revolution!

Epigenetic Editors: CRISPR's Geneless Gene Control Revolution!

How a new delivery system and epigenetic editors control genes without cutting DNA

Marco Lolaico
Marco Lolaico
AI protein designAI protein design
AI-Designed Enzyme Engineering: Machine Learning Catalyzes Biotech Breakthroughs!

AI-Designed Enzyme Engineering: Machine Learning Catalyzes Biotech Breakthroughs!

How catalytic motifs and protein backbones can be assembled into functional enzymes from scratch

Marco Lolaico
Marco Lolaico
DNA/RNA nanotechDNA/RNA nanotech
DNA Trivalent Binders: DNA Nanotechnology Meets Viral Geometry!

DNA Trivalent Binders: DNA Nanotechnology Meets Viral Geometry!

Evolving trivalent DNA binders to match viral protein geometry

Marco Lolaico
Marco Lolaico
2025 Wrapped

2025 Wrapped

The "best" articles of the year!

Marco Lolaico
Marco Lolaico
Synthetic BiologySynthetic Biology
+1+1
AI-Designed DNA Binders: Machine Learning Crafts Novel Proteins!

AI-Designed DNA Binders: Machine Learning Crafts Novel Proteins!

Designing sequence-specific DNA-binding proteins entirely from scratch

Marco Lolaico
Marco Lolaico
DNA/RNA nanotechDNA/RNA nanotech
+1+1
DNA Origami Membranes: Molecular Mimicry Rewrites Cellular Architecture!

DNA Origami Membranes: Molecular Mimicry Rewrites Cellular Architecture!

Engineered DNA barrels self-organize into flexible monolayers that behave like synthetic membranes.

Marco Lolaico
Marco Lolaico