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Synthetic Biology

Flexible Nanopores: Nanoscale Sensors Read Proteins of Different Sizes

Sep 3, 2026

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5 min read

Flexible Nanopores: Nanoscale Sensors Read Proteins of Different Sizes

A flexible nanopore changes shape to sense proteins across multiple sizes and conformations.

Marco Lolaico

Genome Editing Tools

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RNA-Targeting Cas12a2: CRISPR's Deadly New Cell-Killing Weapon

Aug 27, 2026

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5 min read

RNA-Targeting Cas12a2: CRISPR's Deadly New Cell-Killing Weapon

Cas12a2 turns target RNA recognition into genome-wide DNA damage, selectively triggering cell death.

Marco Lolaico

DNA/RNA Nanotech

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Bio-Inspired DNA Origami: Programmable Nanomachines Pierce Cell Membranes

Aug 20, 2026

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5 min read

Bio-Inspired DNA Origami: Programmable Nanomachines Pierce Cell Membranes

A programmable DNA origami machine mechanically pierces membranes to create a temporary transport pathway.

Marco Lolaico

Deep Tech Breakdowns

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Recoded E. coli: Constructive Bio Transforms Biomanufacturing with Synthetic Genomes

Aug 16, 2026

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8 min read

Recoded E. coli: Constructive Bio Transforms Biomanufacturing with Synthetic Genomes

A radically recoded bacterial genome creates room for non-canonical amino acids in biological production.

Marco Lolaico

AI for Genome

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AI-Designed Phages: Machine Learning Creates Viral Genomes!

Aug 13, 2026

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6 min read

AI-Designed Phages: Machine Learning Creates Viral Genomes!

Genome language models generate complete phage genomes that can actually infect and kill bacteria.

Marco Lolaico

DNA/RNA Nanotech

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AI-Designed DNA Origami: Generative AI Tackles Nanotech!

Aug 6, 2026

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5 min read

AI-Designed DNA Origami: Generative AI Tackles Nanotech!

By training on simulated DNA origami structures, AI learns to design complex geometries despite limited experimental data.

Marco Lolaico

Genome Editing Tools

KNIT Genome Editing: A New Designed Tool for Safer Gene Therapy!

Jul 30, 2026

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6 min read

KNIT Genome Editing: A New Designed Tool for Safer Gene Therapy!

A new genome editing platform physically tethers donor DNA to Cas9 for safer and more efficient gene insertion for therapeutic applications.

Marco Lolaico

Deep Tech Breakdowns

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Polymer-Peptides Hybrids: Grove Biopharma Targets Undruggable Diseases!

Jul 26, 2026

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6 min read

Polymer-Peptides Hybrids: Grove Biopharma Targets Undruggable Diseases!

Grove Biopharma uses protein-like polymers to deliver peptides inside cells, opening the door to drug targets that have long been considered unreachable.

Marco Lolaico

DNA/RNA Nanotech

DNA Origami Vaccines: Next-Gen Immune Response!

Jul 23, 2026

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5 min read

DNA Origami Vaccines: Next-Gen Immune Response!

A DNA origami scaffold organizes antigens and immune signals with nanometer precision for stronger and broader antiviral immune responses.

Marco Lolaico

Synthetic Biology

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Protein Crystals: Programming Living Cells as Microreactors!

Jul 16, 2026

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5 min read

Protein Crystals: Programming Living Cells as Microreactors!

Researchers turned living cells into programmable microreactors that grow and functionalize protein crystals.

Marco Lolaico

DNA/RNA Nanotech

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Parallel DNA Synthesis: Chips & Enzymes Speed Up Biotech!

Jul 9, 2026

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5 min read

Parallel DNA Synthesis: Chips & Enzymes Speed Up Biotech!

By combining semiconductor chips and enzymes, researchers synthesized dozens of different DNA sequences in parallel.

Marco Lolaico

Deep Tech Breakdowns

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Cache DNA's Room-Temperature DNA Technology Explained!

Jul 5, 2026

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7 min read

Cache DNA's Room-Temperature DNA Technology Explained!

Analyzing Cache DNA's room-temperature nucleic acid preservation technology: what's validated, what's proprietary, and what we still don't know

Marco Lolaico

Archive

Flexible Nanopores: Nanoscale Sensors Read Proteins of Different Sizes

RNA-Targeting Cas12a2: CRISPR's Deadly New Cell-Killing Weapon

Bio-Inspired DNA Origami: Programmable Nanomachines Pierce Cell Membranes

Recoded E. coli: Constructive Bio Transforms Biomanufacturing with Synthetic Genomes

AI-Designed Phages: Machine Learning Creates Viral Genomes!

AI-Designed DNA Origami: Generative AI Tackles Nanotech!

KNIT Genome Editing: A New Designed Tool for Safer Gene Therapy!

Polymer-Peptides Hybrids: Grove Biopharma Targets Undruggable Diseases!

DNA Origami Vaccines: Next-Gen Immune Response!

Protein Crystals: Programming Living Cells as Microreactors!

Parallel DNA Synthesis: Chips & Enzymes Speed Up Biotech!

Cache DNA's Room-Temperature DNA Technology Explained!

Plenty of Room