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Dive into the collection of past posts to discover timeless content!

Deep Tech Breakdowns

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DNA-Powered Spatial Biology: Sequencers Replaces Microscopes!

Sep 13, 2026

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9 min read

DNA-Powered Spatial Biology: Sequencers Replaces Microscopes!

Instead of imaging cells with a microscope, Pixelgen encodes spatial information in DNA and reconstructs protein organization from sequencing data.

Marco Lolaico
Marco Lolaico

Drug Delivery

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AI-Designed RNA Shuttles: Synthetic Protein Vehicles for Drug Delivery

Sep 10, 2026

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6 min read

AI-Designed RNA Shuttles: Synthetic Protein Vehicles for Drug Delivery

By combining AI-designed proteins with natural membrane and RNA-binding modules, researchers built synthetic vehicles for RNA delivery.

Marco Lolaico
Marco Lolaico

Synthetic Biology

Flexible Nanopores: Nanoscale Sensors Read Proteins of Different Sizes

Sep 3, 2026

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5 min read

Flexible Nanopores: Nanoscale Sensors Read Proteins of Different Sizes

A flexible nanopore changes shape to sense proteins across multiple sizes and conformations.

Marco Lolaico
Marco Lolaico

Genome Editing Tools

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RNA-Targeting Cas12a2: CRISPR's Deadly New Cell-Killing Weapon

Aug 27, 2026

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5 min read

RNA-Targeting Cas12a2: CRISPR's Deadly New Cell-Killing Weapon

Cas12a2 turns target RNA recognition into genome-wide DNA damage, selectively triggering cell death.

Marco Lolaico
Marco Lolaico

DNA/RNA Nanotech

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Bio-Inspired DNA Origami: Programmable Nanomachines Pierce Cell Membranes

Aug 20, 2026

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5 min read

Bio-Inspired DNA Origami: Programmable Nanomachines Pierce Cell Membranes

A programmable DNA origami machine mechanically pierces membranes to create a temporary transport pathway.

Marco Lolaico
Marco Lolaico

Deep Tech Breakdowns

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Recoded E. coli: Constructive Bio Transforms Biomanufacturing with Synthetic Genomes

Aug 16, 2026

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8 min read

Recoded E. coli: Constructive Bio Transforms Biomanufacturing with Synthetic Genomes

A radically recoded bacterial genome creates room for non-canonical amino acids in biological production.

Marco Lolaico
Marco Lolaico

AI for Genome

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AI-Designed Phages: Machine Learning Creates Viral Genomes!

Aug 13, 2026

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6 min read

AI-Designed Phages: Machine Learning Creates Viral Genomes!

Genome language models generate complete phage genomes that can actually infect and kill bacteria.

Marco Lolaico
Marco Lolaico

DNA/RNA Nanotech

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AI-Designed DNA Origami: Generative AI Tackles Nanotech!

Aug 6, 2026

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5 min read

AI-Designed DNA Origami: Generative AI Tackles Nanotech!

By training on simulated DNA origami structures, AI learns to design complex geometries despite limited experimental data.

Marco Lolaico
Marco Lolaico

Genome Editing Tools

KNIT Genome Editing: A New Designed Tool for Safer Gene Therapy!

Jul 30, 2026

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6 min read

KNIT Genome Editing: A New Designed Tool for Safer Gene Therapy!

A new genome editing platform physically tethers donor DNA to Cas9 for safer and more efficient gene insertion for therapeutic applications.

Marco Lolaico
Marco Lolaico

Deep Tech Breakdowns

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Polymer-Peptides Hybrids: Grove Biopharma Targets Undruggable Diseases!

Jul 26, 2026

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6 min read

Polymer-Peptides Hybrids: Grove Biopharma Targets Undruggable Diseases!

Grove Biopharma uses protein-like polymers to deliver peptides inside cells, opening the door to drug targets that have long been considered unreachable.

Marco Lolaico
Marco Lolaico
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