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Oliver Buchannon
Marco Lolaico

DNA nanotech researcher, writing Plenty of Room to always bring you the coolest papers!

Synthetic Biology

+1

Protein Crystals: Programming Living Cells as Microreactors!

Jul 16, 2026

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5 min read

Protein Crystals: Programming Living Cells as Microreactors!

Researchers turned living cells into programmable microreactors that grow and functionalize protein crystals.

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Parallel DNA Synthesis: Chips & Enzymes Speed Up Biotech!

Jul 9, 2026

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5 min read

Parallel DNA Synthesis: Chips & Enzymes Speed Up Biotech!

By combining semiconductor chips and enzymes, researchers synthesized dozens of different DNA sequences in parallel.

Marco Lolaico
Marco Lolaico

Deep Tech Breakdowns

+2

Cache DNA's Room-Temperature DNA Technology Explained!

Jul 5, 2026

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7 min read

Cache DNA's Room-Temperature DNA Technology Explained!

Analyzing Cache DNA's room-temperature nucleic acid preservation technology: what's validated, what's proprietary, and what we still don't know

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

AI-Designed Metalloenzymes: Machine Learning Creates Nature-Level Catalysts!

Jul 2, 2026

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5 min read

AI-Designed Metalloenzymes: Machine Learning Creates Nature-Level Catalysts!

By combining quantum chemistry with generative AI, researchers designed metal-dependent enzymes that approach the efficiency of nature's own catalysts.

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Simplified Bacterial Cells: New Weapons Against Antibiotic-Resistant Superbugs!

Jun 25, 2026

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5 min read

Simplified Bacterial Cells: New Weapons Against Antibiotic-Resistant Superbugs!

Scientists turn chromosome-free bacterial particles into programmable weapons against antibiotic-resistant pathogens

Marco Lolaico
Marco Lolaico

Synthetic Biology

AI-Designed 19-Letter Cells: Rewriting Life's Protein Alphabet!

Jun 18, 2026

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5 min read

AI-Designed 19-Letter Cells: Rewriting Life's Protein Alphabet!

Researchers rebuilt ribosomal proteins with a reduced 19-amino-acid alphabet.

Marco Lolaico
Marco Lolaico

Synthetic Biology

+1

AI-Designed Protein Cages: Virus-Inspired Nanocages Unlocked!

Jun 11, 2026

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5 min read

AI-Designed Protein Cages: Virus-Inspired Nanocages Unlocked!

Virus-inspired design unlocks giant, programmable protein nanocages.

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Synthetic Cell Reactors: DNA Nanopores Engineer Cell Chemistry!

Jun 4, 2026

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5 min read

Synthetic Cell Reactors: DNA Nanopores Engineer Cell Chemistry!

DNA nanopores coordinate transport, signaling, and chemistry inside artificial cells.

Marco Lolaico
Marco Lolaico

Genome Editing Tools

DNA Rewires CRISPR: Cas12 Becomes RNA-Sensing Platform!

May 28, 2026

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6 min read

DNA Rewires CRISPR: Cas12 Becomes RNA-Sensing Platform!

Pseudo-guide DNA turns Cas12 into a versatile platform for RNA sensing and knockdown.

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Designer RNA Nanostars: Programming Membraneless Organelles!

May 21, 2026

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5 min read

Designer RNA Nanostars: Programming Membraneless Organelles!

RNA nanostars assemble membraneless organelles with tunable composition and behavior.

Marco Lolaico
Marco Lolaico

Synthetic Biology

+1

AI-Designed Protein Switches: ML Creates Allosteric Biosensors!

May 14, 2026

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6 min read

AI-Designed Protein Switches: ML Creates Allosteric Biosensors!

Researchers turn AI-designed binders into allosteric protein switches, creating sensors, logic gates, and programmable cellular responses.

Marco Lolaico
Marco Lolaico

Synthetic Biology

Designed Protein Recorders: Cells Build 3D Memory!

May 7, 2026

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5 min read

Designed Protein Recorders: Cells Build 3D Memory!

A protein-based recorder grows 3D structures inside cells, turning transient signals into molecular "tree-rings" you can image later.

Marco Lolaico
Marco Lolaico

Drug delivery

+1

DNA Logic Meets Affibodies: DNA Circuits Enable Smart Drug Delivery!

Apr 30, 2026

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6 min read

DNA Logic Meets Affibodies: DNA Circuits Enable Smart Drug Delivery!

Researchers combine affibodies with programmable DNA circuits to deliver drugs only when the right markers align.

Marco Lolaico
Marco Lolaico

AI protein design

AI-Designed Ultra Strong Proteins: Unbreakable at 150°C!

Apr 23, 2026

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5 min read

AI-Designed Ultra Strong Proteins: Unbreakable at 150°C!

AI-guided design packs force-bearing protein strands with extra hydrogen bonds for extreme stability.

Marco Lolaico
Marco Lolaico

Synthetic Biology

Computer-Powered Virtual Cells: 4D Simulations Model Life at Molecular Level!

Apr 16, 2026

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5 min read

Computer-Powered Virtual Cells: 4D Simulations Model Life at Molecular Level!

A 4D whole-cell model simulates cellular processes across space and time with molecular detail.

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Molecular Hard Drives: DNA Origami Rewrites Data Storage!

Apr 9, 2026

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10 min read

Molecular Hard Drives: DNA Origami Rewrites Data Storage!

DNA origami structures act as storage nodes, encoding data and connections at the nanoscale.

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Synthetic DNA Cells: Synthetic Cytoskeleton Engineering!

Apr 2, 2026

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10 min read

Synthetic DNA Cells: Synthetic Cytoskeleton Engineering!

Synthetic DNA cells recreate the crowded and viscoelastic environment of the cytoplasm.

Marco Lolaico
Marco Lolaico

AI for genome

AI-Designed Genomes: Evo 2 Unlocks Genome-Scale DNA!

Mar 26, 2026

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10 min read

AI-Designed Genomes: Evo 2 Unlocks Genome-Scale DNA!

Trained on trillions of DNA bases, a genomic foundation model predicts mutations and generates new genomes.

Marco Lolaico
Marco Lolaico

Drug delivery

+1

mRNA-Launched Vaccines: mRNA and Protein Nanostructures for Immune Breakthrough!

Mar 19, 2026

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9 min read

mRNA-Launched Vaccines: mRNA and Protein Nanostructures for Immune Breakthrough!

mRNA-launched vaccines merge intracellular expression with the potency of protein nanostructures.

Marco Lolaico
Marco Lolaico

Synthetic Biology

Biological Quantum Sensors: Fluorescent Proteins Transform Biology!

Mar 12, 2026

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10 min read

Biological Quantum Sensors: Fluorescent Proteins Transform Biology!

Directed evolution converts a fluorescent protein into a genetically encoded quantum sensor.

Marco Lolaico
Marco Lolaico

Drug delivery

+1

DNA Origami Boosts Anti-HIV Antibodies: Vaccine Breakthrough!

Mar 5, 2026

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10 min read

DNA Origami Boosts Anti-HIV Antibodies: Vaccine Breakthrough!

DNA origami enhances production of rare anti-HIV antibodies by rewiring immune competition.

Marco Lolaico
Marco Lolaico

Genome Editing Tools

+1

Armored Viruses: Mineral Shells Deliver RNA Editors to Treat Sepsis!

Feb 26, 2026

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10 min read

Armored Viruses: Mineral Shells Deliver RNA Editors to Treat Sepsis!

Mineral shells help viruses evade immunity, deliver RNA editors, and treat sepsis in mice

Marco Lolaico
Marco Lolaico

DNA/RNA nanotech

+1

Designer RNA Tiles: Programmable Nanostructures Inside Cell Nuclei!

Feb 19, 2026

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8 min read

Designer RNA Tiles: Programmable Nanostructures Inside Cell Nuclei!

Programmable RNA structures assemble inside living cell nuclei

Marco Lolaico
Marco Lolaico

Synthetic Biology

RNA TimeVaults: Capturing Cellular Decision Dynamics!

Feb 12, 2026

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9 min read

RNA TimeVaults: Capturing Cellular Decision Dynamics!

A molecular hard drive engineered to store RNA states in living cells.

Marco Lolaico
Marco Lolaico

Synthetic Biology

Sidewinder Rewrites DNA Assembly Rules With Designed DNA Junctions!

Feb 5, 2026

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10 min read

Sidewinder Rewrites DNA Assembly Rules With Designed DNA Junctions!

A new assembly method builds complex DNA without sequence or length constraints

Marco Lolaico
Marco Lolaico
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